TABLE 1

Effects of cortisone treatment on plasma levels of GCs in lean and DIO mice

Plasma samples were collected 5 days after sham operation or cortisone pellet implantation into lean and DIO mice. Values are mean ± S.E.M. (lean, n = 5; lean/CP, n = 5; DIO, n = 16; and DIO/CP, n = 28).

Treatment GroupCortisoneCortisol11-DHCCorticosterone
nM
LeanN.D.N.D.N.D.N.D.
Lean/CP202 ± 12.9314 ± 29.2N.D.N.D.
DION.D.N.D.N.D.55 ± 13.4
DIO/CP135 ± 8.4284 ± 20.7N.D.N.D.
  • N.D., Not detected.