Systolic blood pressure, heart rate, and blood hemoglobin levels in the experimental groups at day 14
| Dose | Blood Pressure | Heart Rate | Hemoglobin | |
|---|---|---|---|---|
| mg/kg per day | mm Hg | bpm | g/dl | |
| Control | 120 ± 3.5 | 350 ± 15 | 14 ± 0.3 | |
| Indomethacin | 3 | 115 ± 3 | 371 ± 17 | 11.6 ± 0.1* |
| Indomethacin + omeprazole | 3 | 114 ± 5 | 372 ± 15 | 11.8 ± 1.2* |
| Diclofenac | 8 | 118 ± 3.8 | 352 ± 8.9 | 12.1 ± 0.6* |
| Diclofenac + omeprazole | 8 | 116 ± 3 | 355 ± 11 | 11.9 ± 0.8* |
| Etoricoxib | 5 | 125 ± 4.2 | 345 ± 11 | 12.6 ± 0.4 |
| Celecoxib | 4 | 121 ± 2.15 | 350 ± 12 | 13.8 ± 0.5 |
↵* P < 0.05, significant difference vs. control