Prostaglandin E2 content in the small intestine
| Treatment of 14 Days | Prostaglandin E2 | ||
|---|---|---|---|
| Jejunum | Ileum | ||
| mg/kg per day | ng/g tissue | ||
| Control | 148 ± 12 | 129 ± 10 | |
| Indomethacin | 3 | 96 ± 11* | 77 ± 9* |
| Indomethacin + omeprazole | 3 | 93 ± 3* | 79 ± 6* |
| Diclofenac | 8 | 101 ± 6* | 68 ± 7* |
| Diclofenac + omeprazole | 8 | 94 ± 4* | 74 ± 5* |
| Etoricoxib | 5 | 134 ± 7 | 130 ± 5 |
| Celecoxib | 4 | 139 ± 8 | 131 ± 6 |
↵* P < 0.05, significant difference vs. control