TABLE 2

Estimated parameters and goodness-of-fit for different solutes in accord with Scheme 1 (fluorescein and mannitol) and Scheme 2 (tobramycin) in the IPRL Absorption Studies with F_a = 0.75

Blank cells for k₁₂ and k₂₁ indicate data consistent with Scheme 1.

	Dose	k_a	k₁₂	k₂₁	k₁₂/k₂₁	r²	MSC
	mg	min⁻¹
Tobramycin	0.002	0.0651	0.1639	0.0184	8.91	0.9998	6.04
	0.02	0.0660	0.1307	0.0205	6.38	0.9998	6.06
	0.2	0.0695	0.0905	0.0223	4.06	0.9999	6.89
	2	0.0700	0.0721	0.0214	3.37	0.9999	6.82
Mannitol	0.02	0.0184				0.9896	2.25
Mannitol	2	0.0198				0.995	3.45
Fluorescein	0.02	0.0761				0.9988	4.8

MSC, model selection criterion.