Control | Collagen I (50 μg/ml) | |||
---|---|---|---|---|
Emax | pEC50 | Emax | pEC50 | |
g | −log M | g | −log M | |
Vehicle | 35.0 ± 3.4 | 6.54 ± 0.09 | 24.6 ± 2.8* | 6.33 ± 0.03 |
PF-573228 (100 nM) | 32.6 ± 2.2 | 6.53 ± 0.13 | 32.9 ± 1.7** | 6.53 ± 0.15 |
Emax, maximal contraction; EC50, concentration of agonist eliciting half-maximal response; pEC50, negative logarithm of the EC50 value.
↵*P < 0.05 compared with vehicle-treated control; **P < 0.05 compared with collagen I–treated control (vehicle).