TABLE 1

Values of maximal relaxation (Rmax) and pD2 to acetylcholine and sodium-nitroprusside in control, NaClO-exposed and DMOG-treated aortic rings

Values represent mean ± S.E.M.

VariableControlNaOClDMOG 10−4M
Rmax to Ach (%)95 ± 144 ± 4 #68 ± 5#*
pD2 to Ach7.23 ± 0.16.46 ± 0.116.20 ± 0.44 #
Rmax to SNP (%)101 ± 1101 ± 1100 ± 1
pD2 to SNP8.26 ± 0.068.11 ± 0.068.33 ± 0.10
KCl (g)3.83 ± 0.152.52 ± 0.20 #2.74 ± 0.20 #
Phenylephrine (g)3.25 ± 0.153.45 ± 0.153.10 ± 0.16
  • SNP, sodium nitroprusside

  • # versus NaOCl; P < 0.05.

  • * versus control.