ED50 values for AM4054 administered alone (baseline) or after pretreatment with various doses of SR141716A and AM4113
Values are given in milligrams per kilogram.
| SR141716A | ED50 | AM4113 | ED50 |
|---|---|---|---|
| Baseline | 0.004 | Baseline | 0.004 |
| 0.03 | 0.006 | 0.32 | 0.019 |
| 0.1 | 0.014 | 1.0 | 0.036 |
| 0.3 | 0.017 | 3.2 | 0.168 |
| 1.0 | 0.095 | 5.6 | 0.164 |