Effects of PNU-120596 on motor coordination of mice
The effects of PNU-120596 (4 and 8 mg/kg i.p.) on the Rotarod test after administration in mice. Fifteen minutes after injection with either PNU-120596 or vehicle, mice were placed on the Rotarod for 3 minutes. Data are presented as the mean ± S.E. of six to eight mice.
| Percentage Impairment | |
|---|---|
| Vehicle | 10.2 ± 10.2 |
| PNU-120596 (4 mg/kg) | 17.2 ± 17.2 |
| PNU-120596 (8 mg/kg) | 11.0 ± 11.0 |