TABLE 1

Characteristics of concentration-response curves

Group−Log EC50Emax
Sham8.64 ± 0.0970.1 ± 1.1
IH8.70 ± 0.0577.4 ± 0.7 *
Sham + Go69768.88 ± 0.1069.2 ± 1.0
IH + Go69768.68 ± 0.0574.4 ± 2.2
Sham + Go69838.80 ± 0.0769.0 ± 2.2
IH + Go69838.70 ± 0.1149.1 ± 3.7 * #
Sham + rottlerin8.64 ± 0.0865.7 ± 2.0
IH + rottlerin8.45 ± 0.0643.2 ± 4.6 * #
Sham + OSU-030128.41 ± 0.0571.7 ± 1.72
IH + OSU-030128.41 ± 0.15#57.2 ± 2.0 * #

  • IH, intermittent hypoxia.

  • ↵* P < 0.05 vs. respective sham treatment

  • ↵# P < 0.05 vs. IH.