TABLE 1

Effects of menthol on the voltage dependency of I_Na and Ica activation and inactivation

Values are means ± S.E.

	Sample	Activation			Inactivation
	Sample	V_1/2	k	n	V_1/2	k	n
I_Na	Prementhol	−36.4 ± 3.0	2.3 ± 0.4	6	−42.2 ± 2.8	4.4 ± 0.2	6
	Menthol	−33.8 ± 2.9	3.2 ± 0.4	6	−52.8 ± 2.5^*	4.6 ± 0.6	6
I_Ca	Prementhol	−3.9 ± 2.2	4.4 ± 0.1	7	−18.7 ± 5.1	16.8 ± 1.3	6
	Menthol	1.1 ± 2.1^*	5.1 ± 1.2	7	−27.0 ± 6.0^*	18.5 ± 1.7	6

n, number of neurons; V_1/2, voltage of half-maximal activation or inactivation; k, slope factor.
↵* P < 0.05 compared with prementhol.