TABLE 1
Comparative biological activity of STA-9122 and CA4 (IC
50
values, nM)
Compound
Endothelial Cell Capillary Tube Disruption
Endothelial Cell Cytotoxicity
Primary Cell Cytotoxicity Panel
CA4
10
175
N.D.
STA-9122
4
30
47,500–84,100
N.D., not determined.