TABLE 1 Effect of Sar-Met-SP on AP waveform and excitability in type I neurons
AP overshoot is amplitude greater than 0 mV; AP duration is at 0 mV; AP rate of rise and fall are maximal velocities. AHP amplitude is measured from resting potential; τAHP is time constant of decay of the AHP. Rheobase is the minimum depolarizing current injection (picoamperes) to evoke an AP. Comparisons between control and during Sar-Met-SP application were performed with paired t tests. Number of neurons for each comparison is indicated in parentheses.