TABLE 1

Ki values for KGA-2727 and phlorizin against human and rat SGLTs

Data are presented as the means ± S.E.M. (n = 6 or 7).

CompoundHumanRat
SGLT1SGLT2SGLT1SGLT2
nM
KGA-272797.4 ± 42.313,600 ± 740043.5 ± 26.017,100 ± 9900
Phlorizin233 ± 8319.6 ± 4.3210 ± 6441.0 ± 11.9