Ki values for NDP-MSH binding experiments
No significant differences were observed between corresponding pKi values for the wild-type versus variant receptors (p > 0.05).
| Receptor | Ki | pKi |
|---|---|---|
| nM | ||
| WT | 3.9 | 8.46 ± 0.15 |
| V60L | 2.2 | 8.70 ± 0.12 |
| R163Q | 2.8 | 8.56 ± 0.07 |
| F196L | 4.2 | 8.35 ± 0.11 |