TABLE 2

Chronic nicotine treatment does not affect dopamine transport in nucleus accumbens shell

Dopamine transporter densities were determined using ¹²⁵I-RTI-121 autoradiography as described under Materials and Methods. To calculate dopamine uptake rate, constant signals from the voltammetry experiments were fit to a one-phase exponential decay. Care was taken to fit portions of the decaying phase of each dopamine signal where the amount of release matched in both treatment groups. Each value represents the mean ± S.E.M. of 6 to 10 animals per group.