Reaction Measured | Enzyme Activity in Placenta | |
---|---|---|
Nonsmokers | Cigarette Smokers | |
nmol product/g placenta/h | ||
Benzo[a]pyrene hydroxylation | 0.7 ± 0.1 | 28 ± 8 |
3-Methyl-4-monomethylaminoazobenzene N-demethylation | <4 | 26 ± 5 |
Zoxazolamine hydroxylation | 0.4 ± 0.1 | 6 ± 2 |
7-Ethoxycoumarin O-dealkylation | 29 ± 3 | 46 ± 5 |
Each value is the mean ± S.E. The data were obtained from Welch et al. (1968, 1969) and Kapitulnik et al. (1976).