Hematology in GK rats
Results shown are mean ± S.D.
| Day | Number of Rats | Group | Measurement | |||
|---|---|---|---|---|---|---|
| RBC | Hb | Hct | HbA1c | |||
| × 106 cell | g/dl | % | % | |||
| 0 | 7 | Placebo | 7.8 ± 0.4 | 15.8 ± 0.9 | 50.0 ± 2.8 | 4.94 ± 0.24 |
| 6 | Low dose | 6.6 ± 1.4 | 13.1 ± 2.9 | 42.3 ± 9.3 | 4.75 ± 0.14 | |
| 7 | High dose | 7.2 ± 0.8 | 14.4 ± 1.6 | 46.0 ± 5.3 | 4.80 ± 0.19 | |
| 25 | 7 | Placebo | 8.6 ± 0.9 | 16.1 ± 1.7 | 51.1 ± 7.4 | 5.19 ± 0.14 |
| 6 | Low dose | 8.9 ± 0.2 | 16.6 ± 0.5 | 53.8 ± 1.6 | 4.95 ± 0.15** | |
| 7 | High dose | 8.3 ± 0.6 | 15.4 ± 1.2 | 49.8 ± 3.7 | 4.86 ± 0.27** | |
| 42 | 7 | Placebo | 9.0 ± 0.7 | 16.2 ± 1.2 | 53.4 ± 3.8 | 5.41 ± 0.22 |
| 5 | Low dose | 9.0 ± 0.5 | 16.3 ± 1.2 | 53.4 ± 2.8 | 5.20 ± 0.22 | |
| 7 | High dose | 9.4 ± 0.2 | 17.0 ± 0.5 | 54.1 ± 2.2 | 5.19 ± 0.20* | |
| 84 | 7 | Placebo | 9.8 ± 0.8 | 17.9 ± 0.4 | 58.1 ± 1.6 | 6.89 ± 1.61 |
| 5 | Low dose | 9.3 ± 0.8 | 16.7 ± 1.6 | 54.8 ± 4.9 | 5.86 ± 0.64 | |
| 7 | High dose | 9.8 ± 0.1 | 17.8 ± 0.2 | 57.7 ± 0.6 | 5.61 ± 0.32* | |