Baseline MAP and HR values before and after pretreatment with different drugs that were administered before intracisternal WIN55212-2 or its vehicle
Values are means ± S.E.M.
| Treatment | n | MAP | HR | ||
|---|---|---|---|---|---|
| Before | After | Before | After | ||
| mm Hg | beats/min | ||||
| Saline + vehicle | 6 | 115.0 ± 6.0 | 113.3 ± 5.0 | 395 ± 12 | 400 ± 12 |
| Saline + 15 μg WIN55212-2 | 8 | 113.3 ± 5.0 | 115.0 ± 3.0 | 370 ± 10 | 368 ± 17 |
| NPLA + 15 μg WIN55212-2 | 8 | 111.3 ± 3.0 | 112.0 ± 3.0 | 375 ± 10 | 363 ± 13 |
| NPLA + vehicle | 5 | 113.0 ± 4.0 | 110.0 ± 4.0 | 398 ± 16 | 390 ± 20 |