TABLE 3

mRNA levels of proinflammatory mediators in HIF-1βLysMCre⁻ and HIF-1βLysMCre⁺ mice after BDL

HIF-1βLysMCre⁻ and HIF-1βLysMCre⁺ mice were subjected to sham operation or BDL. Ten days after surgery, mRNA levels were quantified by real-time PCR. Data are expressed as mean ± SEM; n = 8.

Gene Name/Function	Sham Operation		BDL
Gene Name/Function	HIF-1βLysMCre⁻	HIF-1βLysMCre⁺	HIF-1βLysMCre⁻	HIF-1βLysMCre⁺
KC	1.0 ± 0.2	2.4 ± 1.0	8.3 ± 1.9^{^a}	8.2 ± 0.8^{^a}
MIP-2	1.0 ± 0.3	2.9 ± 1.1	14.2 ± 0.3^{^a}	20.6 ± 0.3^{^a}
TNF-α	1.2 ± 0.6	1.2 ± 0.4	4.7 ± 1.0^{^a}	3.4 ± 0.7^{^a}

↵a Significantly different (p < 0.05) from sham-operated mice.