Effect of PSMB5 mutations on proteasome subunit composition
Data presented are the mean of three separate experiments ± S.D.
| Cell Line | β5 | LMP7 | β2 | MECL1 | β1 | LMP2 |
|---|---|---|---|---|---|---|
| ng subunit/μg total protein | ||||||
| THP1/WT | 2.5 ± 1.3 | 5.7 ± 1.8 | 5.7 ± 0.7 | 3.1 ± 0.7 | 5.6 ± 0.7 | 3.3 ± 0.7 |
| THP1/BTZ50 | 7.3 ± 2.4 | 4.9 ± 2.9 | 10.6 ± 1.9 | 2.9 ± 1.4 | 10.4 ± 1.6 | 1.0 ± 0.5 |
| THP1/BTZ500 | 5.7 ± 1.9 | 3.5 ± 1.7 | 11.1 ± 3.8 | 2.6 ± 1.7 | 11.7 ± 1.8 | 0.5 ± 0.2 |