P450 mRNA levels relative to GADPH mRNA in liver tissues and leukocytes of the donors
The values are the mRNA ratio × 10−3.
| P450 mRNA Level | Minimum | Maximum | |
|---|---|---|---|
| Median ± QD | |||
| CYP1A2 | |||
| Liver | 89.2 ± 55.15 | 3.92 | 678.3 |
| Leukocytes | 0.419 ± 0.5026 | 0.0168 | 4.78 |
| CYP2B6 | |||
| Liver | 57.91 ± 42.80 | 10.9 | 607.1 |
| Leukocytes | 3.26 ± 4.643 | 0.00454 | 166.1 |
| CYP2C9 | |||
| Liver | 453.8 ± 237.32 | 30.4 | 1853.2 |
| Leukocytes | 0.0178 ± 0.01031 | 0.00022 | 0.0982 |
| CYP2C19 | |||
| Liver | 179.9 ± 130.14 | 10.17 | 1635.8 |
| Leukocytes | 0.0057 ± 0.0056 | 0.000048 | 0.0761 |
| CYP2D6 | |||
| Liver | 219.7 ± 132.86 | 67.92 | 1274.6 |
| Leukocytes | 5.68 ± 40.63 | 0.148 | 16056 |
| CYP3A4 | |||
| Liver | 484.7 ± 406.8 | 2.31 | 4316.9 |
| Leukocytes | 0.0362 ± 0.0184 | 0.000009 | 0.218 |