Length of Treatment | Treatment | Dose | Number of VCMs per 5 Min | |
---|---|---|---|---|
Control | Haloperidol | |||
mg/kg | ||||
Single dose | Vehicle | 0.4 ± 0.3 | 20.4 ± 5.1# | |
Nicotine | 0.1 | 0 ± 0 | 19.1 ± 4.6# | |
Vehicle | 0.4 ± 0.2 | 15.8 ± 4.7# | ||
Nicotine | 0.3 | 0 ± 0 | 13.1 ± 3.4# | |
Once daily for 4 days | Vehicle | 0 ± 0 | 17.9 ± 5.7# | |
Nicotine | 0.1 | 0.2 ± 0.2 | 16.8 ± 4.5# | |
Vehicle | 0.8 ± 0.4 | 15.4 ± 3.9# | ||
Nicotine | 0.2 | 0.2 ± 3.8 | 17.4 ± 3.6# |
↵Significance of difference from own control, # P < 0.05 using two-way ANOVA followed by a Bonferroni's post hoc test.