TABLE 2

pA2 values and slope factors (slope ± S.E.M.) calculated from characterization studies in the mouse prostate gland by the range of muscarinic antagonists used to carbachol

AntagonistSlope ± S.E.M.pA2± S.E.M.
Atropine0.92 ± 0.049.07 ± 0.02
Darifenacin1.02 ± 0.249.08 ± 0.07
4-DAMP1.01 ± 0.359.02 ± 0.11
Himbacine0.98 ± 0.067.19 ± 0.02
Methoctramine0.95 ± 0.186.20 ± 0.06
Pirenzepine1.25 ± 0.386.88 ± 0.09
p-F-HHSiD1.16 ± 0.057.39 ± 0.05
HHSiD0.91 ± 0.217.85 ± 0.07