Potency of AZD9668 for human NE and other serine proteases
| Serine Protease | Replicates | pIC50 |
|---|---|---|
| Mean ± S.E.M. | ||
| NE, human | 5 | 7.9 ± 0.12 |
| Proteinase-3, human | 4 | <4.6 |
| Cathepsin G, human | 5 | <5.1 |
| Chymotrypsin, bovine | 3 | <4.5 |
| Pancreatic elastase, porcine | 5 | <4.6 |
| Trypsin, bovine | 5 | <4.6 |