Effects of HL66 on cytotoxicity of M21, A375.S2, A431, CH27, HSC-3, and Hep3B cells
Cells were treated with HL66 for 24 h. After incubation, the viable cells were measured by Trypan blue exclusion assay. The IC50 (half maximal inhibitory concentration) value of HL66 was determined from dose-response curve. All results are expressed as the mean percentage of control ± S.D. of triplicate determinations from four independent experiments.
| Cell Line | IC50 |
|---|---|
| μM | |
| M21 (human malignant melanoma) | 0.033 ± 0.005 |
| A375.S2 (human malignant melanoma) | 0.043 ± 0.004 |
| A431 (human epidermoid carcinoma) | 0.083 ± 0.010 |
| CH27 (human lung cancer cell line) | 0.053 ± 0.006 |
| HSC-3 (human oral cancer cell line) | 0.041 ± 0.003 |
| Hep3B (human liver cancer cell line) | 1.350 ± 0.122 |