TABLE 2

Plasma cotinine levels in lesioned mice receiving chronic nicotine

Cotinine levels were measured in mouse plasma 16 weeks after the initiation of maintenance level of nicotine in the drinking water. Cotinine levels were not detectable in saccharin-treated mice. Values represent the mean ± S.E.M. of the indicated number of animals.

GroupNo. of MiceCotinine Level
ng/ml
Wild-type10195.0 ± 44
β2(−/−)10203.1 ± 58