TABLE 3

The kinetic parameters for the rate of electron transfer from CPR to the ferric CYP2B6.4 to CYP2B6.9 polymorphic variants

k1 and k2 are rate constants for the fast and slow phases, respectively, and A1 and A2 are their respective relative amplitudes. The data were averaged from two separate measurements with S.D. <10%.

CYP2B6Kinetic Parameters
A1k1A2k2
%s1%s1
CYP2B6.1230.31670.04
CYP2B6.4780.04220.01
CYP2B6.5510.13490.02
CYP2B6.6360.11640.04
CYP2B6.7660.08540.02
CYP2B6.81000.01
CYP2B6.980.42920.04