TABLE 1

Subject demography

Data are presented as mean (S.D.), mean (range) for age.

HNS (n = 6)Smokers (n = 6)COPD (n = 10)
Sex, male/female1/53/35/5
Age, years36 (23–46)43 (35–53)62 (47–74)
FEV12.97 (0.84)3.67 (0.88)1.96 (0.6)
FEV1 predicted101.5 (13.1)107.0 (9.0)74.4 (21.8)
FEV1/FVC, %81.0 (6.6)76.7 (5.2)56.2 (9.9)
Pack year history015.947.1
ICS use, %0070
LABA use, %0050
LAMA use, %0020
Current smokers, %010070
  • LABA, long-acting β-agonist; LAMA, long-acting muscarinic antagonist; ICS, inhaled corticosteroid; FEV, forced expiratory volume; FVC, forced vital capacity.