Treatments | PDE4 Activity | ||
---|---|---|---|
Experiment 1 | Experiment 2 | Experiment 3 | |
pmol cAMP hydrolyzed/min/mg protein (% relative to UT) | |||
UT | 13.76 (100) | 10.49 (100) | 9.14 (100) |
LPS (100 ng/ml) | 24.11 (175.2) | 16.13 (153.8) | 17.88 (195.6) |
SAM (0.75 mM) | 9.38 (68.2) | 8.81 (84) | 5.31 (58.1) |
SAM (0.75 mM) + LPS | 17.92 (130.3) | 12.87 (122.7) | 10.02 (109.6) |