Physiological parameters of animal groups
Results are given as mean ± S.E.M.
| Control | Diabetes | |||||
|---|---|---|---|---|---|---|
| Vehicle (n = 11) | A192621 (n = 3) | Bosentan (n = 8) | Vehicle (n = 11) | A192621 (n = 8) | Bosentan (n = 8) | |
| Body weight, g | 485 ± 16 | 406 ± 2# | 418 ± 7# | 352 ± 6* | 320 ± 5*# | 333 ± 5*# |
| Systolic blood pressure, mm Hg | 129 ± 5 | 159 ± 5# | 142 ± 6 | 142 ± 3 | 157 ± 6# | 157 ± 6 |
| Diastolic blood pressure, mm Hg | 92 ± 3 | 100 ± 4# | 95 ± 5 | 89 ± 5 | 100 ± 5# | 96 ± 3 |
| Blood glucose, mg/dl | 108 ± 4 | 104 ± 5 | 93 ± 9 | 161 ± 17* | 152 ± 8* | 194 ± 27* |