Drug | Cav1.2 | Cav1.3 | ||||||
---|---|---|---|---|---|---|---|---|
CON r200 | Drug r200 | Per. Dec. | n | CON r200 | Drug r200 | Per. Dec. | n | |
% | % | |||||||
30/10 μM Diltiazem | 0.53 ± 0.03 | 0.45 ± 0.06 | 15 ± 7 | 3 | 0.73 ± 0.06 | 0.76 ± 0.05 | −5 ± 4 | 4 |
30 μM Diazepam | 0.49 ± 0.09 | 0.26 ± 0.08** | 50 ± 7 | 4 | 0.68 ± 0.07 | 0.49 ± 0.07* | 28 ± 5 | 3 |
30 μM Flurazepam | 0.35 ± 0.09 | 0.25 ± 0.07* | 31 ± 4 | 4 | 0.79 ± 0.07 | 0.64 ± 0.10 | 19 ± 6 | 3 |
30 μM Desalkylflurazepam | 0.36 ± 0.08 | 0.26 ± 0.07* | 30 ± 5 | 3 | 0.49 ± 0.07 | 0.35 ± 0.08** | 32 ± 7 | 6 |
30 μM Allopregnanolone | 0.50 ± 0.08 | 0.24 ± 0.06*** | 56 ± 5 | 5 | 0.66 ± 0.11 | 0.57 ± 0.11* | 15 ± 3 | 3 |
0.3/1 mM Pentobarbital | 0.44 ± 0.10 | 0.19 ± 0.06* | 58 ± 5 | 3 | 0.69 ± 0.09 | 0.37 ± 0.11** | 49 ± 8 | 4 |
300 mM Ethanol | 0.29 ± 0.12 | 0.12 ± 0.05 | 62 ± 4 | 3 | 0.54 ± 0.04 | 0.45 ± 0.04** | 16 ± 2 | 3 |