Inhibitory effects of AZL, olmesartan, and valsartan on AII-stimulated production of IP1
Data in parentheses are 95% confidence intervals.
| Compound | IC50 | Ratio: Washout (+)/Washout (−) | |
|---|---|---|---|
| Washout (−) | Washout (+) | ||
| nM | |||
| AZL | 9.2 (7.5–10.6) | 81.3 (49.4–133.8) | 9 |
| Olmesartan | 12.2 (10.7–14.0) | 908.5 (424.8–2019.1) | 74 |
| Valsartan | 59.8 (48.1–74.2) | 22,664.4 (13673.6–39909.5) | 379 |