TABLE 2

Dosing protocols for the antiepileptic and antiepileptogenic studies

DayCRS Dosea
Antiepileptic StudybAntiepileptogenesis Studyc
mg/kg
145, 70 8060d, 100
280107
390114
495122
5105129
6115136
7130143
8151
9158
10165
11165
12165
13165
14165
  • a CRS was administered orally each day at 7AM, 3 PM, and 11 PM at the indicated doses.

  • b CRS administration began on postinjury week 5 and/or 17.

  • c CRS administration began 15 min after FPI.

  • d Administered intraperitoneally.