Amino acids identified at the SP-A-TLR4 interface
| Molecule | Amino Acid | Residue No. | K-Fade Confidence | K-Con Confidence |
|---|---|---|---|---|
| TLR4 (human TLR4) | Val (V) | 33 | 1 | 1 |
| Ile (I) | 36 | 0.6 | 0.92 | |
| Arg (R) | 382 | 1 | 1 | |
| Glu (E) | 425 | 1 | 1 | |
| Gln (Q) | 430 | 0.93 | 0.92 | |
| Glu (E) | 474 | 0.9 | 1 | |
| Lys (K) | 477 | 0.94 | 0.83 | |
| Phe (F) | 500 | 1 | 0.91 | |
| SP-A (rat-SP-A) | Gly (G) | 123 | 1 | 1 |
| Gln (Q) | 124 | 1 | 1 | |
| Tyr (Y) | 161 | 1 | 1 | |
| Asp (N) | 177 | 0.92 | 1 | |
| Ser (S) | 187 | 1 | 0.85 | |
| Tyr (Y) | 188 | 1 | 0.81 | |
| Thr (T) | 189 | 0.91 | 0.82 | |
| Pro (P) | 193 | 1 | 1 | |
| Gly (G) | 194 | 1 | 1 |