Gene list of mRNAs significantly altered in mouse striatum after genetic disruption of PDE10A activity, after correction for multiple comparisons
Genes represented in bold were reported to be cAMP-responsive genes by Zhang et al. (2005).
| Gene Symbol | Gene Name | KO vs. WT | Affymetrix ID | |
|---|---|---|---|---|
| FDR P value | Fold Change | |||
| Mm0.405423 | Mus musculus adult male corpus striatum cDNA, RIKEN clone:C030023B07 | 0.00 | 2.95 | 1460043_at |
| Pdyn | Prodynorphin | 0.00 | 2.61 | 1416266_at |
| Gnb4 | G protein, β4 | 0.02 | 2.37 | 1439632_at |
| Nnat | Neuronatin | 0.00 | 2.36 | 1423506_a_at |
| Hist2 h3c2 | Histone 2, H3c2 | 0.03 | 2.31 | 1422155_at |
| Hist1 h4e | Histone 1, H4e | 0.00 | 2.16 | 1422948_s_at |
| Hist1 h4j | Histone 1, H4j | 0.02 | 2.12 | 1428014_at |
| Gnb4 | G protein, β4 | 0.01 | 2.11 | 1419469_at |
| Histh3 h3 | Histone 3, H3 | 0.01 | 2.06 | 1460314_s_at |
| Hist1 h4b | Histone 1, H4b | 0.01 | 1.94 | 1424854_at |
| Gnb4 | G protein, β4 | 0.02 | 1.92 | 1419470_at |
| Crem | cAMP responsive element modulator | 0.03 | 1.90 | 1449037_at |
| BC022623 | cDNA sequence BC022623 | 0.00 | 1.83 | 1426734_at |
| Rab3c | RAB3C, member RAS oncogene family | 0.01 | 1.83 | 1449494_at |
| Dusp14 | Dual-specificity phosphatase 14 | 0.04 | 1.75 | 1431422_a_at |
| Hist1 h2bd | Histone 1, H2b5 | 0.02 | 1.70 | 1452540_a_at |
| Slc7a8 | Solute carrier family 7 (cationic amino acid transporter, y + system), member 8 | 0.00 | 1.63 | 1417929_at |
| Hist1 h2bc | Solute carrier family 7 (cationic amino acid transporter, y + system), member 8 | 0.05 | 1.57 | 1418072_at |
| Sema3e | Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.03 | 1.55 | 1427673_a_at |
| Trim17 | Tripartite motif-containing 17 | 0.05 | 1.50 | 1440932_at |
| Chmp1b | Chromatin modifying protein 1B | 0.00 | 1.49 | 1418817_at |
| Zdhhc14 | Zinc finger, DHHC domain containing 14 | 0.05 | 1.48 | 1423668_at |
| Dgat2 | Diacylglycerol O-acyltransferase 2 | 0.03 | 1.46 | 1422678_at |
| Rab3c | RAB3C, member RAS oncogene family | 0.01 | 1.46 | 1435047_at |
| Tmem41a | Transmembrane protein 41a | 0.00 | 1.42 | 1424191_a_at |
| 2610002M06Rik | RIKEN cDNA 2610002M06 gene | 0.03 | 1.42 | 1418816_at |
| Esd | Esterase D/formylglutathione hydrolase | 0.00 | 1.38 | 1417825_at |
| Abca3 | ATP-binding cassette, sub-family A (ABC1), member 3 | 0.04 | 1.37 | 1451731_at |
| Slc3a1 | Solute carrier family 3, member 1 | 0.05 | 1.37 | 1448741_at |
| Avpi1 | Arginine vasopressin-induced 1 | 0.03 | 1.36 | 1423122_at |
| Mef2d | Myocyte enhancer factor 2D | 0.03 | 1.29 | 1437300_at |
| Dctn3 | Dynactin 3 | 0.05 | 1.28 | 1416247_at |
| Asph | Aspartate-β-hydroxylase | 0.05 | 1.27 | 1433906_at |
| Tmem49 | Transmembrane protein 49 | 0.04 | 1.26 | 1423722_at |
| Znrf1 | Zinc and ring finger 1 | 0.03 | 1.26 | 1424384_a_at |
| Cbx4 | Chromobox homolog 4 (Drosophila Pc class) | 0.01 | 1.24 | 1419583_at |
| Slc3a2 | Solute carrier family 3 member 2 | 0.01 | 1.24 | 1425364_a_at |
| Ppp2r5b | Protein phosphatase 2, regulatory subunit B (B56), β isoform | 0.02 | 1.24 | 1426811_at |
| Trak1 | Trafficking protein, kinesin binding 1 | 0.04 | 1.19 | 1428327_at |
| Reps2 | RALBP1 associated Eps domain containing 2 | 0.04 | 1.19 | 1435389_at |
| Tmem33 | Transmembrane protein 33 | 0.02 | 1.16 | 1436028_at |
| Atp5d | ATP synthase, H + transporting, mitochondrial F1 complex, δ subunit | 0.03 | 1.15 | 1423716_s_at |
| Ckap5 | Cytoskeleton-associated protein 5 | 0.04 | −1.19 | 1442271_at |
| Ubxn2b | UBX domain protein 2B | 0.04 | −1.24 | 1430816_at |
| 2310069P03Rik | RIKEN cDNA 2310069P03 gene | 0.04 | −1.25 | 1441006_at |
| Pard6g | Par-6 partitioning defective 6 homolog gamma (Caenorhabditis elegans) | 0.04 | −1.28 | 1420851_at |
| Taf1d | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41 kDa | 0.05 | −1.30 | 1457292_at |
| Hla-dma | Major histocompatibility complex, class II, DM α | 0.03 | −1.36 | 1422527_at |
| Rnf144a | Ring finger protein 144A | 0.00 | −1.37 | 1438404_at |
| Chat | Choline acetyltransferase | 0.03 | −1.37 | 1443372_at |
| Cgref1 | Cell growth regulator with EF hand domain1 | 0.02 | −1.38 | 1424529_s_at |
| Eif2c4 | Eukaryotic translation initiation factor 2C, 4 | 0.01 | −1.39 | 1453289_at |
| BM119687.2 | Mouse newborn kidney cDNA library (Long) Mus musculus cDNA clone NIA:L0929D02 | 0.04 | −1.39 | 1447060_at |
| Eif2c4 | Eukaryotic translation initiation factor 2C, 4 | 0.03 | −1.39 | 1429779_at |
| Clca6 | Chloride channel calcium activated 6 | 0.01 | −1.42 | 1443256_at |
| Gm715 | Gene model 715 | 0.01 | −1.45 | 1445503_at |
| Kcns2 | K+ voltage-gated channel, subfamily S, 2 | 0.02 | −1.46 | 1457325_at |
| Mm0.402736 | Transcribed locus | 0.05 | −1.48 | 1458052_at |
| Id4 | Inhibitor of DNA binding 4 | 0.04 | −1.48 | 1423260_at |
| Id4 | Inhibitor of DNA binding 4 | 0.02 | −1.59 | 1450928_at |
| Rps6ka5 | Ribosomal protein S6 kinase, polypeptide 5 | 0.01 | −1.62 | 1440343_at |
| Fst | Follistatin | 0.03 | −1.62 | 1434458_at |
| C030009J22Rik | RIKEN cDNA C030009J22 gene | 0.02 | −1.64 | 1458386_at |
| 1110032E23Rik | RIKEN cDNA 1110032E23 gene | 0.01 | −1.72 | 1416805_at |
| Ptprv | Protein tyrosine phosphatase, receptor type, V | 0.00 | −1.74 | 1449957_at |
| Neu2 | Neuraminidase 2 | 0.04 | −1.83 | 1431936_a_at |
| 1110032E23Rik | RIKEN cDNA 1110032E23 gene | 0.00 | −2.24 | 1429637_at |
| Clspn | Claspin homolog (Xenopus laevis) | 0.00 | −2.55 | 1456280_at |