Neutrophil recruitment as measured by MPO activity in colons of wild-type and cytokine-null mice
Values are the mean ± S.E.M. (n = 8). Numbers lacking any asterisks are not significantly different, and all data have been tested down to 0.001. Differences between wild-type and cytokine-deficient mice were determined by t test.
| Colon MPO Activity | ||
|---|---|---|
| Control | Infected | |
| units/mg protein | ||
| WT | 3.48 ± 0.78 | 6.54 ± 0.98* |
| IL6(−/−) | 3.26 ± 0.67 | 2.95 ± 0.60 |
| IFNγ(−/−) | 1.94 ± 0.28 | 12.1 ± 2.05** |