TABLE 1
Effect of 5-HT3 receptor antagonists on serotonin activation of SP response in NG-108-15 cells
EC50 values correspond to the results shown in Fig. 1. GraphPad Prism was used to obtain EC50 values (sigmoidal dose-response variable slope). Errors correspond to ± S.E.M. Data are the average of at least eight independent determinations. EC50 for SP + 5-HT + palonosetron was statistically different with P < 0.001 compared with SP + 5-HT by using Student's t test.