Table 2

Depletion of B cells from normal donor PBMC samples with the afucosylated anti-CD19 mAb MEDI-551 and the anti-CD20 mAb rituximab

Donor	MEDI-551 EC₅₀ (95% CI)	R²	Rituximab EC₅₀ (95% CI)	R²
	nM		nM
343	0.016 (0.0096–0.0264)	0.991	0.431 (0.2158–0.8625)	0.975
310	0.014 (0.0073–0.0251)	0.970	0.252 (0.2166–0.2947)	0.998
374	0.029 (0.0132–0.0645)	0.968	0.063 (0.0500–0.0802)	0.989
421	0.0006 (0.0003–0.0011)	0.896	0.032 (0.0240–0.0416)	0.989
442	0.003 (0.0005–0.0183)	0.989	0.018 (0.0157–0.0208)	0.825
467	0.0007 (0.0001–0.0055)	0.957	0.039 (0.0348–0.0442)	0.992