Average number of serotonergic neurons per electrode descent in the dorsal raphe
A descent consisted of lowering a single-barreled electrode over a 1-mm distance from the floor of the Sylvius aqueduct and recording spontaneously firing 5-HT neurons. The numbers in parentheses correspond to the number of descents in each group.
| Group | 2 Days | Post-WAY-100635 |
|---|---|---|
| Control | 4.9 ± 0.5 (15) | |
| Trazodone (5 mg/kg) | 5.5 ± 0.6 (14) | |
| Trazodone (10 mg/kg) | 4.2 ± 0.7 (10) | 4.7 ± 0.7 (7) |
| Trazodone (20 mg/kg) | 1.7 ± 0.3 (11)* | 4.2 ± 0.8 (6) |
↵* P < 0.01.