Dosages and number of rats per treatment group for the static allodynia PD study
| Group | No. of Rats | Day 1 |
|---|---|---|
| 1 | 12 | Saline loading dose and continuous infusion |
| 2 | 12 | 2-h pregabalin infusion at 4 mg·kg−1·h−1 |
| Saline loading dose and continuous infusion | ||
| 3 | 12 | 2-h pregabalin infusion at 10 mg·kg−1·h−1 |
| Sildenafil 2.2-mg loading dose and 12 mg/kg/h continuous infusion | ||
| 4 | 11 | Sildenafil 2.2-mg loading dose and 12 mg/kg/h continuous infusion |
| 5 | 11 | 2-h pregabalin infusion at 1.6 mg·kg−1·h−1 |
| Sildenafil 2.2-mg loading dose and 12 mg/kg/h continuous infusion | ||
| 6 | 10 | 2-h pregabalin infusion at 4 mg·kg−1·h−1 |
| Sildenafil 2.2-mg loading dose and 12 mg/kg/h continuous infusion |