TABLE 1

Food consumption and body weight in the acute or chronic NIH tests

Data are from n = 10 mice.

NIH ParadigmAvg. Amount ConsumedAvg. Body Weight
Home Day 1Home Day 2End of TrainingEnd of Experiment
g± S.D.
Acute
    Saline0.36 ± 0.110.35 ± 0.12N.A.25.6 ± 2.9
    Nicotine0.37 ± 0.150.39-±0.12N.A.26.2 ± 2.7
    Sazetidine-A0.37 ± 0.160.40 ± 0.15N.A.24.9 ± 3.4
    Varenicline0.37 ± 0.120.40 ± 0.20N.A.25.9 ± 2.5
    CDP0.37 ± 0.200.40 ± 0.22N.A.25.7 ± 2.6
Chronic
    Saline0.37 ± 0.200.35 ± 0.1026.9 ± 2.027.6 ± 2.5
    Nicotine0.40 ± 0.200.38-±0.1527.0 ± 2.527.8 ± 2.1
    Sazetidine-A0.41 ± 0.200.35 ± 0.1127.3 ± 2.428.2 ± 2.2
    Varenicline0.40 ± 0.150.40 ± 0.2527.6 ± 2.128.0 ± 2.9
    DMI0.39 ± 0.120.38 ± 0.1526.7 ± 2.127.2 ± 2.4
  • N.A., not applicable.