Inhibitory effects of E3710 and esomeprazole on acid secretion stimulated by db-cAMP and histamine in isolated rabbit gastric glands
Each value represents the mean (95% CI) from four independent experiments performed in duplicate.
| IC50 | ||
|---|---|---|
| db-cAMP | Histamine | |
| μM | ||
| E3710 | 0.40 (0.28–0.59) | 0.27 (0.12–0.58) |
| Esomeprazole | 0.53 (0.29–0.99) | 0.41 (0.22–0.74) |
| Famotidine | >100 | 0.35 (0.25–0.48) |