Group | Drug | Bolus | Infusion |
---|---|---|---|
μmol/kg (mg/kg) | μmol/kg/h (mg/kg/h) | ||
M-1 | Monomer | 0.21 (0.5) | 0.54 (1.25) |
M-1/10 | Monomer | 0.021 (0.05) | 0.054 (0.125) |
M-2* | Monomer | 0.43 (1.0) | 3.1 (2.5) |
M-4 | Monomer | 0.86 (2.0) | 6.2 (5.0) |
D | Dimer | 0.11 (0.5) | 0.27 (1.25) |
DD | Dimer | 0.21 (1.0) | 0.54 (2.5) |
↵* M-2 is not presented in the method of the present study (M-2 is part of an already published group) (Osipov et al., 2009b).