TABLE 1

NAT1 activity and cell proliferation parameter (doubling time, WST-1 reduction, and cell index) of nonconfluent HaCaT cells propagated for at least 48 h in DMEM + 10% FCS

NAT1 Activity (n = 4)Doubling Time (n = 8)WST-1 Reduction (n = 3)Cell Index (n = 3)
nmol/mg/minhOD 450–655 nmarbitrary unit
HaCaT with NAT1 high activity29.8 ± 1.96*21.9 ± 0.42**2.3 ± 0.194.1 ± 0.51
HaCaT with NAT1 low activity13.8 ± 333.6 ± 2.551.6 ± 0.572.8 ± 1.02

  • ↵* Values were significantly different compared with NAT1 low activity with P = 0.021.

  • ↵** Values were significantly different compared with NAT1 low activity with P < 0.001.