Receptor | Receptor Species and Source | Competing Ligand | IC50 |
---|---|---|---|
μM | |||
Muscarinic acetylcholine receptors | |||
M1 | Human recombinant CHO cells | Methylscopolamine | >10 |
M2 | Human recombinant CHO cells | Methylscopolamine | >10 |
M3 | Human recombinant CHO cells | Methylscopolamine | >10 |
Nicotinic acetylcholine receptors | |||
α1 | Human RD cells | α-Bungarotoxin | >3 |
α4β2 | Rat brain | Cytisine | >3 |
α7 | Rat brain | α-Bungarotoxin | >3 |
α7 | Rat brain | Methyllycaconitine | >3 |
Histamine receptor | |||
H3 | Human recombinant CHO-K1 cells | Methylhistamine | >50 |
CHO, Chinese hamster ovary.