TABLE 3

Effect of amphetamine on [¹¹C]raclopride and [¹¹C]NPA BP_P

Values are mean ± S.D.; n = 10 subjects.

Region	[¹¹C]Raclopride BP_P			[¹¹C]NPA BP_P			Δ Ratio, NPA/Raclopride
Region	Baseline	After Amphetamine	Difference	Baseline	After Amphetamine	Difference	Δ Ratio, NPA/Raclopride
			%			%
Ventral striatum	0.98 ± 0.16	0.83 ± 0.20	−16.1 ± 9.5^*	3.42 ± 0.75	2.82 ± 0.87	−18.4 ± 12.9^*	1.14
Caudate	1.01 ± 0.16	0.86 ± 0.18	−14.9 ± 9.4^*	2.86 ± 0.61	2.35 ± 0.64	−18.4 ± 13.7^*	1.23
Putamen	1.33 ± 0.19	1.06 ± 0.19	−20.7 ± 8.9^*	4.09 ± 0.84	3.11 ± 0.84	−24.4 ± 9.4^*	1.18
Striatum	1.18 ± 0.17	0.96 ± 0.18	−18.5 ± 9.0^*	3.58 ± 0.76	2.80 ± 0.75	−22.1 ± 10.5^*	1.19