Effect of L5 vs. prednisolone (Pred) on TG metabolism in adipose tissue-abdominal fat pad
Data shown are mean (S.D.). n = 6 per group.
| Fat Pad Weight | Fractional Replacement of TG | Absolute TG Synthesis | Absolute Lipolysis | DNL-Fractional Replacement of Palmitate | DNL-Absolute Palmitate Synthesis | Glycero-Neogenesis | |
|---|---|---|---|---|---|---|---|
| mg | %/wk | mg/wk | mg/wk | %/wk | mg/wk | % | |
| Vehicle | 313 (32) | 36 (3) | 101 (13) | 118 (16) | 20 (8) | 10.4 (4.8) | 21 (8) |
| Pred 5 mg/kg | 293 (112) | 36 (2) | 93 (37) | 106 (39) | 29 (20) | 10.9 (3.7) | 16 (6) |
| Pred 30 mg/kg | 308 (49) | 32 (1)* | 89 (14) | 109 (17) | 15 (2) | 7.2 (1.6) | 11 (8) |
| L5 5 mg/kg | 358 (74) | 35 (2) | 113 (27) | 119 (29) | 22 (4) | 12.9 (4.6) | 13 (9) |
| L5 30 mg/kg | 402 (69) | 35 (2) | 127 (21) | 131 (20) | 23 (3) | 14.7 (2.9) | 16 (9) |
↵* , P < 0.05 compared with vehicle control.