TABLE 2

Values of apparent kinetic parameters K_m, V_max, and K_m/V_max obtained from incubations of dauricine with human recombinant CYP3A4 or CYP3A5 in the presence of NADPH and GSH

GSH conjugate 3 was monitored by LC/MS/MS. The kinetic data of CYP3A4 are adapted from our previous work (Wang et al., 2009).