Relative contributions of CYP1A2, CYP2C9, CYP2C19, CYP2D6, and CYP3A4 to the metabolism of MLN3897 in human liver microsomes
| P450 | |||||
|---|---|---|---|---|---|
| 2C9 | 1A2 | 2C19 | 2D6 | 3A4 | |
| Fm (%)a | 0 | 4.8 | 0 | 21 | 87 |
↵a fm (%), fractional contribution of specific P450s to the metabolism of MLN3897.