Endocannabinoids | | | |
Anandamide | AEA | N-(2-Hydroxyethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide | Nonselective agonist (CB1>CB2) |
2-Arachidonylglycerol | 2-AG | (5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic acid | Nonselective agonist (CB1>CB2) |
Docosatetraenylethanolamide | DEA | N-(2-Hydroxyethyl)-7Z,10Z,13Z,16Z-docosatetraenamide | Selective CB1 receptor agonist |
Phytocannabinoids | | | |
Cannabidiol | CBD | 2-[(1R,6R)-3-Methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-1,3-benzenediol | Not fully clarified |
Cannabinol | CBN | 6,6,9-Trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol | Nonselective agonist (CB1, CB2) |
Δ9-Tetrahydrocannabinol | THC | (6aR,10aR)-6a,7,8,10a-Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol | Nonselective agonist (CB1, CB2) |
Synthetic cannabinoids | | | |
CP 55,940 | CP 55,940 | (−)-cis-3-[2-Hydroxy-4-(1,1-dimethylheptyl)phenyl]-trans-4-(3-hydroxypropyl)cyclohexanol | Nonselective agonist (CB1, CB2) |
HU-210 | HU-210 | (6aR)-trans-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-6H-dibenzo[b,d]pyran-9-methanol | Nonselective agonist (CB1, CB2) |
HU-331 | HU-331 | 3-Hydroxy-2-[(1R,6R)-3-methyl-6-(1-methylethenyl)-2-cyclohexen-1-yl]-5-pentyl-2,5-cyclohexadiene-1,4-dione | Inhibition of topoisomerase II |
JWH-133 | JWH-133 | (6aR,10aR)-3-(1,1-Dimethylbutyl)-6a,7,10,10a-tetrahydro −6,6,9-trimethyl-6H-dibenzo[b,d]pyran | Selective CB2 receptor agonist |
Met-fluoro-anandamide | Met-F-AEA | 2-Methyl-arachidonyl-2′-fluoro-ethylamide | Nonselective agonist (CB1>CB2) |
Methanandamide | MA | (R)-N-(2-Hydroxy-1-methylethyl)-5Z,8Z,11Z,14Z-eicosatetraenamide | Nonselective agonist (CB1>CB2) |
WIN-55,212-2 | WIN-55,212-2 | (R)-(+)-[2,3-Dihydro-5-methyl-3-(4-morpholinylmethyl)pyrrolo[1,2,3-de]-1,4-benzoxazin-6-yl]-1-naphthalenylmethanone | Nonselective agonist (CB1, CB2) |